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Company ReportsTravere Therapeutics

Travere Therapeutics(TVTX)

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Revenue by Drug

Marketed Drugs

Therapeutic Areas:

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Classification:

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Include Generics:

Trade Name	Drug Name	Approved	Patent Expires	Indication
Kolbam	Cholic acid	2015-11-20		Zellweger syndrome , Inborn errors metabolism
Syntocinon	Oxytocin	1982-01-01		Postpartum hemorrhage
Filspari	Sparsentan	2023-02-17	2030	Proteinuria

Clinical Trials

Therapeutic Areas:

All

Classification:

All

Approval:

All

Status:

All

Phases:

All

Drug Name

Phase 1

Phase 2

Phase 3

Phase 4

Indication

healthy volunteers/patients

,

renal insufficiency

,

,

,

smoldering multiple myeloma

,

,

paraproteinemias

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

lymphoid leukemia

,

,

plasma cell leukemia

,

monoclonal gammopathy of undetermined significance

,

nephrotic syndrome

,

residual neoplasm

,

,

,

non-hodgkin lymphoma

,

hodgkin disease

,

,

aplastic anemia

,

,

bone marrow failure disorders

,

b-cell lymphoma

,

b-cell leukemia

,

glomerulonephritis

,

immune system diseases

,

autoimmune diseases

,

,

hereditary nephritis

,

lipoid nephrosis

,

cardiovascular diseases

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

hematopoietic stem cell transplantation

,

immunoglobulin light-chain amyloidosis

,

multiple myeloma

,

plasma cell neoplasms

,

iga glomerulonephritis

,

focal segmental glomerulosclerosis

,

kidney diseases

,

kidney transplantation

,

,

coronary artery disease

Fosmetpantotenate

nerve degeneration

,

pantothenate kinase-associated neurodegeneration

healthy volunteers/patients

,

gastrointestinal neoplasms

,

follicular lymphoma

,

pancreatic neoplasms

,

hepatocellular carcinoma

,

digestive system neoplasms

,

neoplasm metastasis

,

respiratory tract diseases

,

pleural effusion

,

,

respiratory tract neoplasms

,

bronchogenic carcinoma

,

thoracic neoplasms

,

neoplasms by site

,

malignant pleural effusion

,

pleural diseases

,

pleural neoplasms

,

myeloid leukemia acute

,

,

squamous cell carcinoma of head and neck

,

head and neck neoplasms

,

,

squamous cell carcinoma

,

squamous cell neoplasms

,

multiple myeloma

,

chronic hepatitis c

,

,

,

adenocarcinoma of lung

,

non-small-cell lung carcinoma

,

type 2 diabetes mellitus

,

,

diabetes mellitus

,

colorectal neoplasms

,

,

non-hodgkin lymphoma

,

,

breast neoplasms

,

,

,

pulmonary embolism

,

,

papulosquamous skin diseases

,

essential hypertension

,

restless legs syndrome

,

,

rheumatoid arthritis

,

respiratory distress syndrome

,

vascular access devices

,

catheter obstruction

,

,

ischemic stroke

,

,

type 1 diabetes mellitus

,

,

polycystic kidney diseases

,

,

myocardial infarction

,

,

,

kidney diseases

,

diabetic neuropathies

,

diabetic nephropathies

,

,

idiopathic pulmonary fibrosis

,

pulmonary fibrosis

,

liver cirrhosis

,

parkinson disease

,

peripheral arterial disease

,

intermittent claudication

,

peripheral vascular diseases

,

,

disease progression

,

hypersensitivity

,

extrinsic allergic alveolitis

Globulin, immune

healthy volunteers/patients

,

renal insufficiency

,

,

bites and stings

,

small cell lung carcinoma

,

,

myelodysplastic syndromes

,

thrombocytopenia

,

,

,

bone marrow failure disorders

,

,

electrocardiography

,

transplantation

,

,

hepatic insufficiency

,

male breast neoplasms

,

dermatomyositis

,

inclusion body myositis

,

dna repair-deficiency disorders

,

hereditary congenital and neonatal diseases and abnormalities

,

,

hypoplastic anemia congenital

,

hemic and lymphatic diseases

,

adenosquamous carcinoma

,

,

head and neck neoplasms

,

kidney neoplasms

,

,

squamous cell carcinoma of head and neck

,

esophageal neoplasms

,

squamous cell neoplasms

,

renal cell carcinoma

,

,

,

,

pancreatic neoplasms

,

squamous cell carcinoma

,

mantle-cell lymphoma

,

b-cell lymphoma

,

triple negative breast neoplasms

,

carcinoid tumor

,

type 1 diabetes mellitus

,

aplastic anemia

,

smoldering multiple myeloma

,

gastrointestinal neoplasms

,

urinary bladder neoplasms

,

,

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

philadelphia chromosome

,

hematopoietic stem cell transplantation

,

thyroid neoplasms

,

hodgkin disease

,

endocrine gland neoplasms

,

parathyroid neoplasms

,

,

giant cell tumors

,

second primary neoplasms

,

hemangiosarcoma

,

fracture healing

,

chronic urticaria

,

,

post-traumatic headache

,

,

temporomandibular joint disorders

,

temporomandibular joint dysfunction syndrome

,

mucocutaneous lymph node syndrome

,

cutaneous malignant melanoma

,

b-cell lymphoma marginal zone

,

burkitt lymphoma

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

graft vs host disease

,

ovarian neoplasms

,

fallopian tube neoplasms

,

,

waldenstrom macroglobulinemia

,

urologic neoplasms

,

transitional cell carcinoma

,

ureteral neoplasms

,

serotonin syndrome

,

malignant pleural effusion

,

circulating neoplastic cells

,

biliary tract neoplasms

,

gallbladder neoplasms

,

myelomonocytic leukemia juvenile

,

pleomorphic adenoma

,

replacement arthroplasty hip

,

,

,

aneurysmal bone cysts

,

giant cell granuloma

,

,

chondroblastoma

,

chronic kidney failure

,

,

brain neoplasms

,

kidney transplantation

,

graft rejection

,

psychology rejection

,

kidney diseases

,

iga glomerulonephritis

,

,

invasive hydatidiform mole

,

,

breast neoplasms

,

neoplasm metastasis

,

non-small-cell lung carcinoma

,

rectal neoplasms

,

colonic neoplasms

,

multiple myeloma

,

,

non-hodgkin lymphoma

,

large b-cell lymphoma diffuse

,

,

prostatic neoplasms

,

precursor cell lymphoblastic leukemia-lymphoma

,

castration-resistant prostatic neoplasms

,

,

stomach neoplasms

,

,

,

,

,

plasma cell neoplasms

,

lymphoid leukemia

,

inflammatory breast neoplasms

,

follicular lymphoma

,

mucinous adenocarcinoma

,

,

hematologic neoplasms

,

,

,

osteogenesis imperfecta

,

ductal carcinoma breast

,

spinal cord compression

,

,

,

,

febrile neutropenia

,

musculoskeletal diseases

,

hematologic diseases

,

blood protein disorders

,

,

bone marrow diseases

,

paraproteinemias

,

neoplastic processes

,

multiple endocrine neoplasia type 1

,

,

personal satisfaction

,

,

ankylosing spondylitis

,

homozygous familial hypercholesterolemia

,

human influenza

,

atopic dermatitis

,

,

,

esophageal squamous cell carcinoma

,

phenylketonurias

,

feeding and eating disorders

,

anorexia nervosa

,

,

immunoglobulin g4-related disease

,

,

colorectal neoplasms

,

,

,

rheumatoid arthritis

,

,

metabolic bone diseases

,

postmenopausal osteoporosis

,

,

hyperlipidemias

,

,

psoriatic arthritis

,

hypercholesterolemia

,

giant cell tumor of bone

,

juvenile arthritis

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

,

graves ophthalmopathy

,

,

,

hyperlipoproteinemias

,

diabetes mellitus

,

hyperlipoproteinemia type ii

,

primary hyperparathyroidism

,

,

,

neuromyelitis optica

,

metabolic syndrome

,

insulin resistance

,

autoimmune diseases

,

,

,

,

microvascular angina

,

t-cell lymphoma peripheral

,

coronary artery disease

,

myocardial ischemia

,

atherosclerosis

,

hidradenitis suppurativa

,

thyroid diseases

healthy volunteers/patients

,

metabolic syndrome

,

myelodysplastic syndromes

,

peripheral arterial disease

,

atherosclerosis

,

barrett esophagus

,

insulin resistance

,

autonomic nervous system diseases

,

pure autonomic failure

,

shy-drager syndrome

,

,

postural orthostatic tachycardia syndrome

,

orthostatic intolerance

,

cardiovascular diseases

,

,

,

,

myeloid leukemia acute

,

primary myelofibrosis

,

precursor cell lymphoblastic leukemia-lymphoma

,

b-cell chronic lymphocytic leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

myeloid leukemia

,

,

essential hypertension

,

acute lung injury

,

,

hematologic neoplasms

,

respiratory distress syndrome

,

newborn respiratory distress syndrome

,

cognitive dysfunction

,

,

psychological stress

,

graft vs host disease

,

thrombocytopenia

,

non-hodgkin lymphoma

,

,

hodgkin disease

,

pheochromocytoma

,

coronary artery bypass

,

,

nephrotic syndrome

,

focal segmental glomerulosclerosis

,

metabolic diseases

,

cord blood stem cell transplantation

,

,

,

,

,

,

clear cell sarcoma

,

isolated systolic hypertension

,

multiple myeloma

,

plasma cell neoplasms

,

,

,

,

,

,

,

abdominal obesity

,

renal hypertension

,

dilated cardiomyopathy

,

breast neoplasms

,

wounds and injuries

,

traumatic brain injuries

,

,

,

coronavirus infections

,

,

cardiomyopathies

,

,

communicable diseases

,

respiratory insufficiency

,

hypertrophic cardiomyopathy

,

ischemic stroke

,

,

,

cerebral infarction

,

,

,

,

,

iga glomerulonephritis

,

acute kidney injury

,

,

,

,

,

kidney diseases

,

type 2 diabetes mellitus

,

,

chronic renal insufficiency

,

diabetes mellitus

,

,

white coat hypertension

,

,

,

vascular diseases

,

,

left ventricular hypertrophy

,

hypophosphatemia

,

familial hypophosphatemic rickets

,

renin-angiotensin system

,

pediatric obesity

,

,

type 1 diabetes mellitus

,

kidney diseases

,

cardiovascular diseases

,

,

anti-neutrophil cytoplasmic antibody-associated vasculitis

drug interactions

,

,

,

therapeutic equivalency

,

pure autonomic failure

,

,

peripheral arterial disease

,

autonomic nervous system diseases

,

b-cell lymphoma marginal zone

,

alcohol-related disorders

,

b-cell leukemia

,

,

primary myelofibrosis

,

myelomonocytic leukemia chronic

,

leukemia myeloid chronic atypical bcr-abl negative

,

myeloid leukemia chronic-phase

,

myeloid leukemia accelerated phase

,

,

,

diabetes complications

,

,

multiple system atrophy

,

postural orthostatic tachycardia syndrome

,

orthostatic intolerance

,

pharmacokinetics

,

peripheral vascular diseases

,

,

orthostatic hypotension

,

mitochondrial diseases

,

systemic mastocytosis

,

blastic plasmacytoid dendritic cell neoplasm

,

oral lichen planus

,

,

urinary bladder neoplasms

,

carcinoma in situ

,

glycogen storage disease type ii

,

thrombocytopenic purpura idiopathic

,

viral pneumonia

,

alpha 1-antitrypsin deficiency

,

inborn errors metabolism

,

,

,

,

,

gallbladder diseases

,

,

,

,

asymptomatic diseases

,

bone resorption

,

stress fractures

,

pancreatic ductal carcinoma

,

endomyocardial fibrosis

,

sex characteristics

,

alcohol drinking

,

bile duct neoplasms

,

cholangiocarcinoma

,

biliary tract neoplasms

,

social cognition

,

tissue adhesions

,

,

,

precursor cell lymphoblastic leukemia-lymphoma

,

pancreatic neoplasms

,

hematologic neoplasms

,

myelodysplastic syndromes

,

b-cell chronic lymphocytic leukemia

,

,

b-cell lymphoma

,

,

myeloid leukemia acute

,

hodgkin disease

,

sickle cell anemia

,

,

,

large b-cell lymphoma diffuse

,

lymphoid leukemia

,

bcr-abl positive chronic myelogenous leukemia

,

neoplasm metastasis

,

acquired immunodeficiency syndrome

,

post-traumatic stress disorders

,

hairy cell leukemia

,

squamous cell carcinoma of head and neck

,

graft vs host disease

,

myeloid leukemia

,

mantle-cell lymphoma

,

respiratory distress syndrome

,

myeloproliferative disorders

,

,

cystic fibrosis

,

,

hematologic diseases

,

hypertrophic cardiomyopathy

,

radiation fibrosis syndrome

,

circulating neoplastic cells

,

,

kidney neoplasms

,

,

,

,

respiratory insufficiency

,

obstructive sleep apnea

,

brain neoplasms

,

castration-resistant prostatic neoplasms

,

myelodysplastic-myeloproliferative diseases

,

,

eosinophilic esophagitis

,

,

,

prediabetic state

,

peritoneal neoplasms

,

precursor t-cell lymphoblastic leukemia-lymphoma

,

precursor b-cell lymphoblastic leukemia-lymphoma

,

stomach neoplasms

,

,

prolymphocytic leukemia

,

waldenstrom macroglobulinemia

,

burkitt lymphoma

,

chronic disease

,

,

,

thrombocytopenia

,

t-cell lymphoma

,

t-cell lymphoma peripheral

,

rhabdomyosarcoma

,

systemic scleroderma

,

autoimmune diseases

,

,

restless legs syndrome

,

respiratory tract infections

,

acute liver failure

,

essential tremor

,

,

autistic disorder

,

autism spectrum disorder

,

aplastic anemia

,

,

acute lung injury

,

newborn respiratory distress syndrome

,

hip osteoarthritis

,

psychotic affective disorders

,

,

treatment-resistant schizophrenia

,

mucopolysaccharidosis iv

,

mucopolysaccharidosis vi

,

mucopolysaccharidoses

,

mucopolysaccharidosis i

,

sedentary behavior

,

pulmonary vein stenosis

,

traumatic stress disorders

,

psychological stress

,

ebola hemorrhagic fever

,

right ventricular dysfunction

,

congenital heart defects

,

tetralogy of fallot

,

,

,

connective tissue diseases

,

hermanski-pudlak syndrome

,

oculocutaneous albinism

,

platelet storage pool deficiency

,

,

prehypertension

,

medulloblastoma

,

,

x-linked bulbo-spinal atrophy

,

alveolar soft part sarcoma

,

fallopian tube neoplasms

,

pain management

,

primary headache disorders

,

bronchiolo-alveolar adenocarcinoma

,

bone marrow transplantation

,

homologous transplantation

,

autologous transplantation

,

immune system diseases

,

,

bronchiolitis obliterans syndrome

,

squamous cell neoplasms

,

chronic hepatitis

,

serous cystadenocarcinoma

,

,

,

central nervous system neoplasms

,

,

intestinal neoplasms

,

nervous system neoplasms

,

uveal neoplasms

,

,

plasma cell leukemia

,

refractory anemia with excess of blasts

,

digeorge syndrome

,

,

hypoparathyroidism

,

phenylketonurias

,

immunosuppression therapy

,

mast-cell leukemia

,

malignant pleural effusion

,

abdominal neoplasms

,

small cell carcinoma

,

small cell lung carcinoma

,

psychology rejection

,

,

hemolytic-uremic syndrome

,

,

thrombotic thrombocytopenic purpura

,

thrombocytopenic purpura

,

,

,

residual neoplasm

,

,

,

cocaine-related disorders

,

,

,

cutaneous mastocytosis

,

,

hepatic encephalopathy

,

chemical and drug induced liver injury

,

dystonic disorders

,

,

,

acoustic neuroma

,

immunoglobulin g4-related disease

,

endocardial fibroelastosis

,

blood protein disorders

,

neoplasms by histologic type

,

paraproteinemias

,

,

psychology repression

,

space motion sickness

,

,

,

gastrointestinal neoplasms

,

digestive system neoplasms

,

gastrointestinal stromal tumors

,

oxidative stress

,

squamous cell carcinoma

,

mouth neoplasms

,

oropharyngeal neoplasms

,

laryngeal neoplasms

,

hypopharyngeal neoplasms

,

replacement arthroplasty knee

,

peripheral nervous system diseases

,

diabetic cardiomyopathies

,

mucinous adenocarcinoma

,

,

paroxysmal hemoglobinuria

,

pure red-cell aplasia

,

bone marrow failure disorders

,

,

,

emergence delirium

,

feasibility studies

,

cardiac surgical procedures

,

hospital mortality

,

immunoblastic lymphadenopathy

,

enteropathy-associated t-cell lymphoma

,

intestinal diseases

,

ovarian epithelial carcinoma

,

,

opioid-related disorders

,

treatment adherence and compliance

,

,

,

multiple myeloma

,

non-hodgkin lymphoma

,

plasma cell neoplasms

,

breast neoplasms

,

hyperlipidemias

,

non-small-cell lung carcinoma

,

,

,

marfan syndrome

,

communicable diseases

,

alzheimer disease

,

anxiety disorders

,

multiple sclerosis

,

lupus nephritis

,

,

head and neck neoplasms

,

follicular lymphoma

,

hypercholesterolemia

,

cognitive dysfunction

,

focal segmental glomerulosclerosis

,

colorectal neoplasms

,

ovarian neoplasms

,

,

postoperative pain

,

,

,

knee osteoarthritis

,

,

,

camurati-engelmann syndrome

,

acute kidney injury

,

,

cerebral hemorrhage

,

cerebral small vessel diseases

,

hyperlipoproteinemias

,

disease progression

,

,

membranous glomerulonephritis

,

,

endometrial neoplasms

,

renal cell carcinoma

,

chronic progressive multiple sclerosis

,

,

,

,

,

vascular dementia

,

hypertriglyceridemia

,

,

polycystic kidney diseases

,

nephrotic syndrome

,

bicuspid aortic valve disease

,

thoracic aortic aneurysm

,

pulmonary fibrosis

,

metabolic diseases

,

retinal diseases

,

,

rectal neoplasms

,

colonic neoplasms

,

chronic urticaria

,

esophageal neoplasms

,

relapsing-remitting multiple sclerosis

,

immunologic deficiency syndromes

,

,

post-traumatic headache

,

,

hyperemesis gravidarum

,

parkinson disease

,

severe acute respiratory syndrome-related coronavirus

,

hemorrhagic stroke

,

,

ehlers-danlos syndrome

,

type iv ehlers-danlos syndrome

,

,

,

aortic valve disease

,

idiopathic pulmonary fibrosis

,

metabolic brain diseases

,

pulmonary hypertension

,

ascending aorta dissection

,

,

,

primary hyperoxaluria

,

cardiac arrhythmias

,

smoldering multiple myeloma

,

headache disorders

,

germ cell and embryonal neoplasms

,

,

choriocarcinoma

,

,

endodermal sinus tumor

,

,

uterine cervical neoplasms

,

psychophysiologic disorders

,

somatoform disorders

,

cesarean section

,

deglutition disorders

,

bipolar and related disorders

,

migraine without aura

,

migraine with aura

,

conscious sedation

,

breast carcinoma in situ

,

acute cholecystitis

,

,

acalculous cholecystitis

,

marijuana abuse

,

left ventricular dysfunction

,

ventricular remodeling

,

microvascular angina

,

ventricular dysfunction

,

vascular remodeling

,

exercise tolerance

,

transfusion reaction

,

aortic coarctation

,

,

,

,

agammaglobulinemia

,

primary immunodeficiency diseases

,

,

healthy volunteers/patients

,

essential hypertension

,

kidney diseases

,

type 2 diabetes mellitus

,

,

diabetic nephropathies

,

,

,

diabetes mellitus

,

,

chronic renal insufficiency

,

migraine disorders

,

,

cardiovascular diseases

,

,

,

sleep initiation and maintenance disorders

,

metabolic syndrome

,

,

insulin resistance

,

,

renal insufficiency

,

,

,

iga glomerulonephritis

,

,

,

coronavirus infections

,

postoperative nausea and vomiting

,

atrial fibrillation

,

,

kidney transplantation

,

chronic kidney failure

,

prostatic neoplasms

,

non-alcoholic fatty liver disease

,

,

chronic hepatitis b

,

hypersensitivity

,

,

,

sleep wake disorders

,

,

,

psychomotor agitation

,

,

,

atopic dermatitis

,

,

severe acute respiratory syndrome

,

left ventricular hypertrophy

,

coronary artery disease

,

,

,

rheumatoid arthritis

,

myocardial ischemia

,

wounds and injuries

,

,

systemic lupus erythematosus

,

,

,

glomerulonephritis

,

,

psychotic disorders

,

isolated systolic hypertension

,

depressive disorder

,

,

,

,

sleep apnea syndromes

,

,

systolic murmurs

,

bipolar disorder

,

major depressive disorder

,

,

,

atherosclerosis

,

,

chronic obstructive pulmonary disease

,

,

altitude sickness

,

graft rejection

,

myocardial infarction

,

ischemic stroke

,

glucose intolerance

,

liver transplantation

,

,

hepatic insufficiency

,

,

,

aphthous stomatitis

,

allergic rhinitis

,

nasal obstruction

,

,

,

chronic bronchitis

,

mental disorders

,

abdominal aortic aneurysm

,

aortic aneurysm

,

liver cirrhosis

,

acute coronary syndrome

,

,

coronary disease

,

,

chronic hepatitis c

,

arteriosclerosis

,

type 1 diabetes mellitus

,

diabetic neuropathies

,

pulmonary arterial hypertension

,

patient-controlled analgesia

,

,

,

,

,

anterior cruciate ligament injuries

,

respiratory tract diseases

,

respiration disorders

,

peritoneal dialysis

,

aortic valve stenosis

,

aortic valve insufficiency

,

,

,

respiratory aspiration

,

pharmacogenomic testing

,

ulcerative colitis

,

,

low cardiac output

,

,

abdominal obesity

,

physiological sexual dysfunction

,

continuous ambulatory peritoneal dialysis

,

carotid stenosis

,

,

,

renin-angiotensin system

,

,

alcoholic liver cirrhosis

,

,

,

hyperaldosteronism

,

rectal diseases

,

,

bacterial infections

,

,

,

respiratory hypersensitivity

,

,

,

pathologic constriction

,

spinal stenosis

,

psychiatric emergency services

,

,

,

endoscopic retrograde cholangiopancreatography

,

allergic rhinitis seasonal

,

,

gastroenteritis

,

tension-type headache

,

,

,

pancreatic diseases

,

,

tick-borne encephalitis

,

,

,

,

,

athletic injuries

,

chronic periodontitis

,

heat stress disorders

,

,

recreational drug use

,

diabetic retinopathy

,

,

hepatocellular carcinoma

,

liver neoplasms

,

,

,

,

,

inferior wall myocardial infarction

,

suicidal ideation

,

rotator cuff injuries

,

,

systolic heart failure

,

drug-related side effects and adverse reactions

,

urologic diseases

,

,

,

cardiomyopathies

,

duchenne muscular dystrophy

,

pregnancy-induced hypertension

,

long-term memory

,

short-term memory

,

radiation pneumonitis

,

,

precancerous conditions

,

angina pectoris

,

microcirculation

,

sick sinus syndrome

,

arteriovenous fistula

,

glucose metabolism disorders

,

drug dose-response relationship

,

,

,

,

,

,

,

substance-related disorders

,

,

lymphatic diseases

,

,

,

premature obstetric labor

,

sleep deprivation

,

self-injurious behavior

,

feeding and eating disorders

,

bulimia nervosa

,

,

,

cluster headache

,

minimally invasive surgical procedures

,

,

benign paroxysmal positional vertigo

,

,

,

,

immunologic cytotoxicity

,

wrist fractures

,

acute-on-chronic liver failure

,

chronic hepatitis d

,

,

spinal cord injuries

,

female genital neoplasms

,

shoulder impingement syndrome

,

,

shoulder injuries

,

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