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Travere Therapeutics
Travere Therapeutics
(TVTX)
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Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Kolbam
Cholic acid
2015-11-20
Zellweger syndrome
,
Inborn errors metabolism
Syntocinon
Oxytocin
1982-01-01
Postpartum hemorrhage
Filspari
Sparsentan
2023-02-17
2030
Proteinuria
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Sparsentan
healthy volunteers/patients
,
hypertension
,
vasculitis
,
glomerulonephritis
,
immune system diseases
,
autoimmune diseases
,
iga vasculitis
,
hereditary nephritis
,
lipoid nephrosis
,
cardiovascular diseases
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
iga glomerulonephritis
,
kidney diseases
,
focal segmental glomerulosclerosis
Angiotensin ii
healthy volunteers/patients
,
hypertrophic cardiomyopathy
,
cardiomyopathies
,
headache
,
cluster headache
,
diabetic retinopathy
,
breast neoplasms
,
hyperkalemia
,
migraine disorders
,
migraine without aura
,
migraine with aura
,
aortic valve stenosis
,
pathologic constriction
,
cardiotoxicity
,
retinal diseases
,
proteinuria
,
atrial fibrillation
,
stroke
,
chronic renal insufficiency
,
renal insufficiency
,
hypertension
,
heart failure
,
type 2 diabetes mellitus
,
diabetes mellitus
,
type 1 diabetes mellitus
,
hypertrophy
,
obesity
,
kidney diseases
,
left ventricular dysfunction
,
ventricular dysfunction
,
left ventricular hypertrophy
,
glucose intolerance
,
cohort studies
,
essential hypertension
,
diabetic nephropathies
Txa127
chronic renal insufficiency
,
kidney diseases
,
proteinuria
Fosmetpantotenate
nerve degeneration
,
pantothenate kinase-associated neurodegeneration
Ademetionine
healthy volunteers/patients
,
crush injuries
,
peritoneal neoplasms
,
fallopian tube diseases
,
prostatic neoplasms
,
hypersensitivity
,
stomach neoplasms
,
melanoma
,
lung neoplasms
,
systemic lupus erythematosus
,
kidney neoplasms
,
esophageal neoplasms
,
heart failure
,
immunoglobulin g4-related disease
,
lung diseases
,
interstitial lung diseases
,
immunologic deficiency syndromes
,
common variable immunodeficiency
,
leukemia
,
myeloproliferative disorders
,
myelodysplastic-myeloproliferative diseases
,
neutrophilic leukemia chronic
,
sarcoma
,
rhabdoid tumor
,
chordoma
,
phenylketonurias
,
breast neoplasms
,
squamous cell carcinoma of head and neck
,
colorectal neoplasms
,
adenocarcinoma
,
renal cell carcinoma
,
non-small-cell lung carcinoma
,
small cell lung carcinoma
,
neoplasms
,
rheumatoid arthritis
,
arthritis
,
carcinoma
,
squamous cell carcinoma
,
myocarditis
,
esophageal squamous cell carcinoma
,
atrial fibrillation
,
chronic kidney failure
,
kidney diseases
,
hiv infections
,
ischemia
,
coronary artery disease
,
venous thromboembolism
,
thromboembolism
,
infections
,
acquired immunodeficiency syndrome
,
communicable diseases
,
ulcerative colitis
,
colitis
,
ulcer
,
obesity
,
type 2 diabetes mellitus
,
diabetes mellitus
Sodium chloride
healthy volunteers/patients
,
ebolavirus
,
obesity
,
overweight
,
staphylococcal infections
,
schizophrenia
,
kidney neoplasms
,
insulin resistance
,
dengue
,
osteoarthritis
,
spine osteoarthritis
,
pinta
,
hyperglycemia
,
castration-resistant prostatic neoplasms
,
small cell carcinoma
,
urethral neoplasms
,
transitional cell carcinoma
,
neuroendocrine tumors
,
neuroendocrine carcinoma
,
sarcoma
,
thrombosis
,
venous thrombosis
,
urinary bladder neoplasms
,
renal insufficiency
,
nausea
,
heart failure
,
chronic kidney failure
,
colorectal neoplasms
,
neoplasms
,
invasive hydatidiform mole
,
respiratory syncytial viruses
,
urologic neoplasms
,
infectious skin diseases
,
skin diseases
,
soft tissue infections
,
bacteremia
,
disease progression
,
rheumatoid arthritis
,
arthritis
,
pancreatic neoplasms
,
general anesthesia
,
urinary tract infections
,
pyelonephritis
,
respiratory tract infections
,
photorefractive keratectomy
,
interstitial lung diseases
,
multiple myeloma
,
plasma cell neoplasms
,
non-hodgkin lymphoma
,
lymphoma
,
non-muscle invasive bladder neoplasms
,
carcinoma in situ
,
squamous intraepithelial lesions
,
st elevation myocardial infarction
,
pancreatitis
,
adenosquamous carcinoma
,
carcinoma
,
infections
,
non-small-cell lung carcinoma
,
lung neoplasms
,
communicable diseases
,
melanoma
,
squamous cell carcinoma of head and neck
,
uterine cervical neoplasms
,
adenocarcinoma
,
prostatic neoplasms
,
breast neoplasms
,
small cell lung carcinoma
,
squamous cell carcinoma
,
hepatocellular carcinoma
,
liver neoplasms
,
papillomavirus infections
,
lung diseases
,
fibrosis
,
cystic fibrosis
,
clostridium infections
,
ovarian epithelial carcinoma
,
cytomegalovirus infections
,
renal cell carcinoma
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
stomach neoplasms
,
head and neck neoplasms
,
anesthesia
,
intraabdominal infections
,
condylomata acuminata
,
myocardial infarction
,
infarction
,
pulmonary fibrosis
,
hiv infections
,
uterine cervical dysplasia
,
squamous intraepithelial lesions of the cervix
,
pneumococcal infections
,
essential hypertension
,
bacterial conjunctivitis
,
conjunctivitis
,
peritoneal neoplasms
,
surgical wound infection
,
esophageal squamous cell carcinoma
,
replacement arthroplasty knee
,
replacement arthroplasty hip
,
hip fractures
,
blood coagulation
,
anus neoplasms
,
persistent infection
,
vaginal neoplasms
,
vulvar neoplasms
,
respiratory syncytial virus infections
,
left ventricular dysfunction
,
stroke
,
cardiopulmonary bypass
,
coronary artery bypass
,
ventricular dysfunction
,
keratoconjunctivitis sicca
,
dry eye syndromes
,
eye diseases
,
warts
,
pneumococcal pneumonia
,
asthma
,
obstructive sleep apnea
,
sleep apnea syndromes
,
apnea
,
spondylarthropathies
,
spondylarthritis
,
spondylitis
,
glioblastoma
,
hypertension
,
vomiting
,
ebola hemorrhagic fever
,
neuromuscular blockade
,
ovarian neoplasms
,
diabetes mellitus
,
esophageal neoplasms
,
kidney diseases
,
invasive candidiasis
,
candidiasis
,
type 2 diabetes mellitus
,
herpes zoster
,
postoperative nausea and vomiting
,
covid-19
,
virus diseases
,
chickenpox
,
psoriasis
,
diabetic nephropathies
,
sepsis
,
colitis
,
uterine neoplasms
,
intestinal diseases
,
cough
,
chronic cough
,
metabolic syndrome
,
bipolar disorder
Bevifimod
healthy volunteers/patients
,
hepatic insufficiency
,
esophageal neoplasms
,
hiv infections
,
neuroblastoma
,
small cell lung carcinoma
,
pancreatic ductal carcinoma
,
multiple myeloma
,
plasma cell neoplasms
,
bronchiolitis obliterans syndrome
,
congenital abnormalities
,
chromosome aberrations
,
brain stem neoplasms
,
chronic hepatitis c
,
chronic hepatitis
,
typhoid fever
,
infertility
,
medulloblastoma
,
rhabdoid tumor
,
ependymoma
,
choroid plexus neoplasms
,
primitive neuroectodermal tumors
,
ganglioglioma
,
pinealoma
,
neuroepithelial neoplasms
,
ganglioneuroblastoma
,
neuroectodermal tumors
,
phenylketonurias
,
precursor t-cell lymphoblastic leukemia-lymphoma
,
nasopharyngeal carcinoma
,
ureteral neoplasms
,
pelvic neoplasms
,
adenoid cystic carcinoma
,
metabolic syndrome
,
follicular lymphoma
,
adenocarcinoma
,
pancreatic neoplasms
,
kidney neoplasms
,
recurrence
,
prostatic neoplasms
,
syndrome
,
glioma
,
head and neck neoplasms
,
neurofibromatoses
,
neurofibroma
,
liver neoplasms
,
sarcoma
,
liver diseases
,
neurofibromatosis 1
,
plexiform neurofibroma
,
systemic scleroderma
,
diffuse scleroderma
,
b-cell chronic lymphocytic leukemia
,
meningioma
,
hematologic neoplasms
,
endometrial neoplasms
,
neuroendocrine carcinoma
,
central nervous system neoplasms
,
ovarian neoplasms
,
mantle-cell lymphoma
,
urinary bladder neoplasms
,
squamous cell carcinoma
,
uterine cervical neoplasms
,
myelodysplastic syndromes
,
non-hodgkin lymphoma
,
nervous system neoplasms
,
hypereosinophilic syndrome
,
systemic mastocytosis
,
mastocytosis
,
uveal neoplasms
,
squamous cell carcinoma of head and neck
,
t-cell lymphoma
,
transitional cell carcinoma
,
primary myelofibrosis
,
metaplasia
,
graft vs host disease
,
adenocarcinoma of lung
,
diffuse intrinsic pontine glioma
,
disease progression
,
oligodendroglioma
,
neurofibromatosis 2
,
acoustic neuroma
,
neurilemmoma
,
hodgkin disease
,
islet cell carcinoma
,
hematologic diseases
,
myeloid leukemia accelerated phase
,
preleukemia
,
mast-cell leukemia
,
aggression
,
germ cell and embryonal neoplasms
,
tuberculosis
,
anaplastic thyroid carcinoma
,
t-cell lymphoma peripheral
,
waldenstrom macroglobulinemia
,
castration-resistant prostatic neoplasms
,
gliosarcoma
,
cholangiocarcinoma
,
chronic disease
,
large-cell lymphoma anaplastic
,
plasma cell granuloma
,
diarrhea
,
skin neoplasms
,
neuroma
,
postmenopause
,
gouty arthritis
,
endocrine gland neoplasms
,
virus diseases
,
urogenital neoplasms
,
male genital diseases
,
prostatic diseases
,
abdominal neoplasms
,
male genital neoplasms
,
genital diseases
,
sjogren's syndrome
,
retinitis pigmentosa
,
retinitis
,
synovitis
,
giant cell tumors
,
pigmented villonodular synovitis
,
giant cell tumor of tendon sheath
,
choroidal neovascularization
,
pathologic neovascularization
,
hemangioblastoma
,
von hippel-lindau disease
,
inflammatory breast neoplasms
,
invasive hydatidiform mole
,
multidrug-resistant tuberculosis
,
local neoplasm recurrence
,
t-cell lymphoma cutaneous
,
peutz-jeghers syndrome
,
acute coronary syndrome
,
st elevation myocardial infarction
,
malignant mesothelioma
,
mesothelioma
,
type 1 diabetes mellitus
,
hypoglycemia
,
intestinal neoplasms
,
testicular neoplasms
,
osteosarcoma
,
brain stem infarctions
,
epilepsy
,
sturge-weber syndrome
,
klippel-trenaunay-weber syndrome
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
carcinoma in situ
,
breast diseases
,
multiple hamartoma syndrome
,
hamartoma
,
urologic neoplasms
,
fallopian tube neoplasms
,
t-cell leukemia
,
localized scleroderma
,
myelomonocytic leukemia chronic
,
myelomonocytic leukemia acute
,
myelomonocytic leukemia juvenile
,
ameloblastoma
,
adamantinoma
,
ovarian epithelial carcinoma
,
sickle cell anemia
,
streptococcus agalactiae
,
colorectal neoplasms
,
myeloid leukemia acute
,
lymphoma
,
glioblastoma
,
neoplasm metastasis
,
brain neoplasms
,
hepatocellular carcinoma
,
astrocytoma
,
thyroid neoplasms
,
thyroid diseases
,
chronic urticaria
,
urticaria
,
large b-cell lymphoma diffuse
,
b-cell lymphoma
,
blast crisis
,
triple negative breast neoplasms
,
hypertension
,
colonic neoplasms
,
arthritis
,
carcinoid tumor
,
pulmonary arterial hypertension
,
familial primary pulmonary hypertension
,
fibrosis
,
gastrointestinal neoplasms
,
stomach neoplasms
,
rectal neoplasms
,
meningitis
,
meningococcal meningitis
,
meningococcal infections
,
rheumatoid arthritis
,
organ transplantation
,
graft rejection
,
digestive system neoplasms
,
cutaneous malignant melanoma
,
stomatitis
,
lymphangioleiomyomatosis
,
lupus nephritis
,
nephritis
,
hypersensitivity
,
peanut hypersensitivity
,
multiple sclerosis
,
relapsing-remitting multiple sclerosis
,
interstitial lung diseases
,
seizures
,
lung transplantation
,
malignant carcinoid syndrome
,
serotonin syndrome
,
food hypersensitivity
,
psoriatic arthritis
,
psoriasis
,
muscular atrophy
,
spinal muscular atrophy
,
atrophy
,
mucositis
,
lung diseases
,
idiopathic pulmonary fibrosis
,
pulmonary fibrosis
,
covid-19
,
chronic inducible urticaria
,
infectious skin diseases
,
bacterial skin diseases
,
skin diseases
,
leukemia
,
myeloid leukemia
,
neoplasms
,
bcr-abl positive chronic myelogenous leukemia
,
breast neoplasms
,
carcinoma
,
lung neoplasms
,
non-small-cell lung carcinoma
,
renal cell carcinoma
,
melanoma
,
kidney transplantation
,
philadelphia chromosome
,
lymphoid leukemia
,
neuroendocrine tumors
,
gastrointestinal stromal tumors
,
precursor cell lymphoblastic leukemia-lymphoma
,
sclerosis
,
myeloid leukemia chronic-phase
,
liver transplantation
,
renal insufficiency
,
tuberous sclerosis
,
chronic kidney failure
,
heart transplantation
,
kidney diseases
,
islet cell adenoma
,
infections
,
angiomyolipoma
,
macular degeneration
,
hepatitis c
,
hepatitis
,
hepatitis a
,
autosomal dominant polycystic kidney
,
communicable diseases
,
polycystic kidney diseases
,
arthrogryposis
,
diabetes mellitus
,
tick-borne encephalitis
,
encephalitis
,
immunosuppression therapy
,
cytomegalovirus infections
,
rare diseases
,
large cell carcinoma
,
vascular diseases
,
macular edema
,
edema
,
vision disorders
,
low vision
,
type 2 diabetes mellitus
,
cross-sectional studies
,
viremia
,
polyomavirus infections
,
cryopyrin-associated periodic syndromes
,
polycythemia vera
,
polycythemia
,
heart failure
,
systolic heart failure
,
myocardial infarction
,
inflammation
,
infarction
,
inferior wall myocardial infarction
Pegtibatinase
homocystinuria
Sglt2
healthy volunteers/patients
,
therapeutic equivalency
,
weight loss
,
liver cirrhosis
,
diastolic heart failure
,
asymptomatic diseases
,
hyperuricemia
,
exercise
,
liver diseases
,
body weight
,
inferior wall myocardial infarction
,
covid-19
,
respiratory insufficiency
,
polycystic ovary syndrome
,
syndrome
,
overweight
,
death
,
left ventricular dysfunction
,
st elevation myocardial infarction
,
non-st elevated myocardial infarction
,
ventricular dysfunction
,
type 2 diabetes mellitus
,
diabetes mellitus
,
heart failure
,
chronic renal insufficiency
,
kidney diseases
,
type 1 diabetes mellitus
,
hypertension
,
albuminuria
,
obesity
,
renal insufficiency
,
prediabetic state
,
insulin resistance
,
proteinuria
,
myocardial infarction
,
infarction
,
fibrosis
,
cardiovascular diseases
,
hyperglycemia
,
diabetic nephropathies
,
fatty liver
,
glucose intolerance
,
focal segmental glomerulosclerosis
,
atrial fibrillation
,
inflammation
,
myocarditis
,
endomyocardial fibrosis
,
hypersensitivity
,
kidney function tests
,
left ventricular hypertrophy
,
hypertrophy
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
carotid artery diseases
,
diabetes complications
,
cardiomyopathies
,
diabetic cardiomyopathies
,
systolic heart failure
Farxiga
healthy volunteers/patients
,
therapeutic equivalency
,
weight loss
,
liver cirrhosis
,
diastolic heart failure
,
asymptomatic diseases
,
hyperuricemia
,
exercise
,
liver diseases
,
body weight
,
inferior wall myocardial infarction
,
covid-19
,
respiratory insufficiency
,
polycystic ovary syndrome
,
syndrome
,
overweight
,
death
,
left ventricular dysfunction
,
st elevation myocardial infarction
,
non-st elevated myocardial infarction
,
ventricular dysfunction
,
type 2 diabetes mellitus
,
diabetes mellitus
,
heart failure
,
kidney diseases
,
chronic renal insufficiency
,
type 1 diabetes mellitus
,
hypertension
,
albuminuria
,
obesity
,
renal insufficiency
,
prediabetic state
,
insulin resistance
,
cardiovascular diseases
,
proteinuria
,
myocardial infarction
,
infarction
,
fibrosis
,
hyperglycemia
,
diabetic nephropathies
,
fatty liver
,
glucose intolerance
,
focal segmental glomerulosclerosis
,
atrial fibrillation
,
inflammation
,
myocarditis
,
endomyocardial fibrosis
,
hypersensitivity
,
kidney function tests
,
left ventricular hypertrophy
,
hypertrophy
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
carotid artery diseases
,
diabetes complications
,
cardiomyopathies
,
diabetic cardiomyopathies
,
infections
,
urinary tract infections
,
breast neoplasms
,
urinary bladder neoplasms
,
wounds and injuries
,
chemical and drug induced liver injury
,
acute kidney injury
,
systolic heart failure
,
heart diseases
,
retinal diseases
Bradykinin
kidney diseases
,
cardiovascular diseases
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
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